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Cannabis’s Tissue Culture Moment Has Arrived

“Cannabis is a very tissue culture resistant plant.”

Whether it’s for orchids, berries, or bananas, plant tissue culture has been widely used in agriculture for nearly 40 years to produce uniform and disease-free stock. But when it comes to cannabis, this technology has only emerged within the last few years as scientists working with weed cracked the code of what the plant wants to reproduce successfully at a small scale. Joining in the fight against one of pot’s primary foes, hop latent viroid disease, cannabis tissue culture is a new path forward towards preserving the genetics of one of the most diverse botanicals on the planet. And, while cultivators have been able to get their hands on tissue culture-grown cuts for about eight years, tissue culture clones were made available to the public for the first time through Node Labs at the Emerald Cup Harvest Ball held in December 2022.

“Cannabis is a very tissue culture resistant plant. There are certain plants that are that way,” says Lauren Avenuis, CEO of Node Labs, explaining why it took so long for the technology to become viable for cannabis. “So, like avocados, grape vines, they just don’t like to go into micropropagation. They don’t like that kind of replication. And since cannabis is an annual plant, it likes to grow from a seed, flower, and die.”

The scientists working with Node, a small lab located within an unassuming red barn in rural Petaluma, California, spent years studying tissue culture before discovering the methodology that made stem cell technology for cannabis work. Now that they have, their facility houses an impressive bank of cannabis genetics. It causes a few snickers when I say it aloud, but being inside a room filled with shelves devoted to tissue culture clones, each in their own container, reminds me of being in a pet store aquarium. All the plants are growing within a clear jelly-like substance derived from seaweed called agar, allowing their whole root structure to be seen. They are terrariums that hold the story of pot’s past, present, and future.

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